Long-Term NMDAR Antagonism Correlates Weight Loss With Less Eating
نویسندگان
چکیده
منابع مشابه
Corrigendum: Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype
[This corrects the article on p. 219 in vol. 9, PMID: 26089779.].
متن کاملLong-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype
The role of glutamate N-methyl-D-aspartate receptor (NMDAR) hypofunction has been extensively studied in schizophrenia; however, less is known about its role in anxiety disorders. Recently, it was demonstrated that astrocytic GLT-1 blockade leads to an anxiety-like phenotype. Although astrocytes are capable of modulating NMDAR activity through glutamate uptake transporters, the relationship bet...
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There is a general perception that almost no one succeeds in long-term maintenance of weight loss. However, research has shown that approximately 20% of overweight individuals are successful at long-term weight loss when defined as losing at least 10% of initial body weight and maintaining the loss for at least 1 y. The National Weight Control Registry provides information about the strategies ...
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J. Graham Thomas, MS, and Rena R. Wing, PhD A key problem in the area of weight control is the maintenance of weight loss. Behavioral treatment programs are able to consistently produce weight losses of 7 – 10% of initial body weight at the end of 6 – 12 months of treatment. However, even with ongoing contact, clients often regain the weight, a finding documented by the Diabetes Prevention Pro...
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Any intervention which causes negative energy balance is guaranteed to be efficacious in producing weight loss, which will continue while there is negative energy balance or be maintained as long as the new energy balance is maintained. In clinical practice compliance is rarely 100% so the efficiency of even the most efficacious treatment is usually low. However, recent evidence-based guideline...
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ژورنال
عنوان ژورنال: Frontiers in Psychiatry
سال: 2019
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2019.00015